| List I | List II | ||
| A. | Histones | I. | Loosely packed chromatin |
| B. | Nucleosome | II. | Densely packed chromatin |
| C. | Euchromatin | III. | Positively charged basic proteins |
| D. | Heterochromatin | IV. | DNA wrapped around histone octamer |
| Statement I: | In prokaryotes, the positively charged DNA is held with some negatively charged proteins in a region called nucleoid. |
| Statement II: | In eukaryotes, the negatively charged DNA is wrapped around the positively charged histone octamer to form nucleosome. |
| List-I | List-II | ||
| (a) | Bacteriophage \(\phi \times 174\) | (i) | 48502 base pairs |
| (b) | Bacteriophage lambda | (ii) | 5386 nucleotides |
| (c) | Escherichia coli | (iii) | 3.3 × 109 base pairs |
| (d) | Haploid content human DNA | (iv) | 4.6 × 106 base pairs |
| (a) | (b) | (c) | (d) | |
| 1. | (i) | (ii) | (iii) | (iv) |
| 2. | (ii) | (iv) | (i) | (iii) |
| 3. | (ii) | (i) | (iv) | (iii) |
| 4. | (i) | (ii) | (iv) | (iii) |
With respect to nucleosome, which of the following statements is incorrect ?
| 1. | Nucleosome contains 120 bp of DNA helix. |
| 2. | Nucleosomes are seen as 'beads' on string' under Electron Microscope. |
| 3. | DNA is wrapped around positively charged histone octamer to form nucleosome. |
| 4. | Nucleosome is the repeating unit of chromatin. |
One of the strands of double stranded DNA has base composition as follows: 15% A, 15% T, 40%G and 30%C. What will be the percentage of these bases in the complementary strand ?
1. 15% A, 15% T, 30% G , 40% C
2. 15% A, 30% T, 40% G , 15% C
3. 15% A, 15% T, 40% G , 30% C
4. 15% A, 40% T, 15% G , 30% C
| 1. | 1 | 2. | 3 |
| 3. | 2.5 | 4. | 2 |
| (a) | Euchromatin is loosely packed chromatin. |
| (b) | Heterochromatin is transcriptionally active. |
| (c) | Histone octomer is wrapped by negatively charged DNA in nucleosome. |
| (d) | Histones are rich in lysine and arginine. |
| (e) | A typical nucleosome contains 400 bp of DNA helix. |
| 1. | (a), (c), (e) only | 2. | (b), (d), (e) only |
| 3. | (a), (c), (d) only | 4. | (b), (e) only |
Complete the flow chart on central dogma
| 1. | (a) - Replication; (b) - Transcription; (c) - Translation; (d) - Protein |
| 2. | (a) - Transduction; (b) - Translation; (c) - Replication; (d) - Protein |
| 3. | (a) - Replication; (b) - Transcription; (c) - Transduction; (d) - Protein |
| 4. | (a) - Transcription; (b) - Replication; (c) - Transcription; (d) - Transduction |